We have experience with complex bioreactors to help achieve precise control of temperature, nutrient concentrations, pH, dissolved gases, and more.
Our team has experience in industrial centrifugation disc stacked centrifuges, hermetically sealed centrifuges, gas centrifuges, and more.
We work with systems for ion-exchange chromatography to separate ions and polar molecules reliably, precisely, selectively, and efficiently, all while achieving a low cost of consumables.
We have experience with ultrafiltration systems across life science disciplines to purify and concentrate macromolecular solutions – especially protein solutions.
CIP and SIP
Our team works with clean-in-place (CIP) and steam-in-place (SIP) systems to automate efficient cleaning and sterilization of upstream and downstream production trains.
Our team has expertise in buffer/media preparation and hold. We have worked on complex automated routing and verification to ensure the right material is available at the right point of use every time.
We have experience with formulation procedures made to fit the exact needs of your specific application, with a particular focus on medicine and pharmaceuticals.
We specialize in granulation systems designed to prevent the demixing of components in a given mixture to improve flow characteristics of powders and compaction properties for tablet formation.
We have extensive experience with systems for blending a wide range of excipients with active pharmaceutical ingredients to create final blends used to manufacture solid dosage forms.
Fluid Bed Processing
Our team has experience in fluid bed processing to achieve a medium with many properties and characteristics of normal fluids, such as the ability to free-flow under gravity or to be pumped using fluid technologies.
Hot Melt Extrusion
We have experience with systems that utilize pharmaceutical solid oral dose processing to enable delivery of drugs with poor solubility and bioavailability, applying heat, pressure, and agitation to mix materials together and extrude them through a die.
Industrial Process Automation
Our team’s strong mix of process and automation know-how enables us to take projects from concept and functional requirement through implementation and commissioning, paired with our extensive experience in a wide variety of PLC/HMI and DCS platforms.
Computer System Validation
GMP validation of your automation software and programming can be a labor-intensive task without the proper expertise. Our team is skilled at creating and interpreting system requirements and then turning those requirements into smart and streamlined test protocols that will save your project time and money.
IT/OT System Engineering
With the integration of manufacturing systems and processes with back-end hardware and software for conveying and processing information, operational technology (OT) and information technology (IT) are converging and becoming increasingly the same. To execute a successful project in today's world, your OT team needs to be able to communicate effectively with your IT team – and we can help.
Your industry facility and devices need safe, reliable, and smart power to enable production. Having a well-engineered design package for your industrial project can reduce costs and accelerate installation. From the incoming utility power to the plant floor, we can work with your team and the construction team to ensure the electrons go where they need to go.
Power System Studies
Our team of engineers can perform a comprehensive arc flash analysis and provide facility owners with the information necessary for employees to work safely on electrical equipment while remaining OSHA- and NFPA70E-compliant. Based on the results of the arc flash study, we provide custom arc flash labels for your equipment, updated electrical drawings, and a full report including analysis and recommendations to reduce and/or properly address arc flash hazards.
Project & Construction Management
Challenging projects require superior organization and facilitation of scope, schedule, and budget. Using best practices and standards suited to your project, our team of experienced professionals can help you manage your project during all phases, from planning and scoping to design and construction.
All electrical equipment in your facilities must be approved, identified, listed, or labeled by an OSHA-accredited nationally recognized testing laboratory (NRTL) – or you could be at risk of costly fines and delays. Excel provides expert-led NRTL field evaluations to ensure your sites are compliant today and safe and productive in the long term.
Why Excel Engineering?
Excel is an experienced, dedicated partner that brings a detail-oriented and relationship-driven approach to every project to ensure it exceeds your goals. Here are just a few of the reasons to partner with us to elevate your life sciences facility.
Improved Product Quality
Improved Product Safety
Improved Asset Reliability
Improved Product Life-Cycle Management
Improved Manufacturing Intelligence
NEWS + INSIGHTS
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New Protein Production Facility Control System
A Life Science reagent manufacturer (End-User) in the Twin Cities, MN area determined the need to create a new production facility to produce ancillary material protein products under GMP conditions. Various system components required the development and implementation of a Process Control System (PCS).